All General Settings are stored per user, and they are stored in CRM so users can have their setting follow them if they use a new PC.
The General Settings can also be controlled globally. Please ask your engineer.
Most settings are easy to understand. Here are some extra notes
These settings control the DT Toolbar colors, tooltip duration and opacity, number of columns in the outcomes selector or phone book, and number of Call Tabs
Telephony Provider. The default is SIP. If you change it other settings need to be changed too so change with care.
IE Version You can set this from 7 to 11